Designated as WOAH Reference Laboratory for Brucellosis at 77th WOAH general session in May, 2009.
Dr. Jin-Ju Lee
[Animal and Plant Quarantine Agency]
Bacterial Disease Division
[Animal and Plant Quarantine Agency]
Pathological study of Korean native pregnant cows and fetuses experimentally vaccinated with Brucella abortus RB51 in heifers and challenged with Brucella abortus 2308 in pregnancy(2013-05-16) | |||||
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Part | 동식물위생연구부 | Charger | Moon Her | date | 2013-05-16 |
You Chan Bae, Gye Hyeong Woo, Ha Young Kim, Moon Her, Dong Hee Cho, Suk Chan Jung, Jae Ku Oem, Jae Won Byun, Yi Seok Joo, O Soo Lee, Myoung Heon Lee Korean Journal of Veterinary Public Health, 2012, 36(3), 109-113 Abstract
Bovine brucellosis causes abortion and infertility. The authors conducted this study in order to determine pathological lesions of Korean native cows and fetuses who received experimental vaccination with Brucella abortus RB51 and were challenged with Brucella abortus 2308. Gross and histopathological lesions in endometrium and placenta were observed in cows of the vaccinated group. Twenty-five percent of pregnant cattle in the vaccinated group showed endometritis and placentitis, which was three times lower, compared with the non-vaccinated group. The pathological lesions in the uterus and placenta in both groups were consistent with previous reports. Therefore, vaccination in heifers using Brucella abortus RB51 may not provide adequate protection against infection with Brucella abortus virulent strain. |
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